Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use

US7122654B2 · kind B2 · utility

Assignees

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• Helsinki University Licensing, Ltd. · FI

Inventors

• Marc G. Achen · Melbourne, AU
• Andrew Frederick Wilks · Melbourne, AU
• Steven Stacker · Melbourne, AU
• Kari Alitalo · Helsinki, FI

Key dates

• Filing date: Oct 22, 2002
• Grant date: Oct 17, 2006
• Expiry date: Nov 15, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.