Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
US7125693B2 · kind B2 · utility
44Cited by
32References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2003 |
| Grant date | Oct 24, 2006 |
| Priority date | — |
| Expiry date | Jul 12, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods and compositions for preparing 4-substituted 3-hydroxybutyric acid derivatives by halohydrin dehalogenase-catalyzed conversion of 4-halo-3-hydroxybutyric acid derivatives. The present invention further provides methods and compositions for preparing 4-halo-3-hydroxybutyric acid derivatives by ketoreductase-catalyzed conversion of 4-halo-3-ketobutyric acid derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.