Substituted dipeptides as growth hormone secretagogues

US7125840B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Jeffrey A. Dodge · Indianapolis, US
• Britta Evers · Hamburg, DE
• Louis Nickolaus Jungheim · Indianapolis, US
• Brian S. Muehl · Indianapolis, US
• Gerd Ruehter · Hamburg, DE
• Kenneth Jeff Thrasher · Indianapolis, US

Key dates

• Filing date: Oct 9, 2001
• Grant date: Oct 24, 2006
• Expiry date: Sep 20, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.