Patent · US Expired

L-nucleic acid derivatives and process for the synthesis thereof

US7125983B2 · kind B2 · utility

12Cited by
0References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 2001
Grant dateOct 24, 2006
Priority date
Expiry dateOct 22, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/09
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A novel method has been found to produce 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine as a novel useful intermediate compound. A novel method has been further found to produce thymidine from 2,2′-anhydro-1-(β-L-arabinofuranosyl)thymine. A novel method has been further found to L-2′-deoxyribose derivatives as a useful synthetic intermediate through L-2,2′-anhydro-5,6-dihydrocyclouridine derivative. According to these methods, synthesis of various L-nucleic acid derivatives, synthesis of which has been difficult till now.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.