Expandable biodegradable polymeric stents for combined mechanical support and pharmacological or radiation therapy
US7128755B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 10, 2002 |
| Grant date | Oct 31, 2006 |
| Priority date | — |
| Expiry date | Aug 15, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0067
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An expandable biodegradable polymeric stent is fabricated with biodegradable polymer fibers (Poly-L-lactic acid, PLLA) in a coil shape that is constructed with both central and external or internal peripheral lobes. It is delivered and expanded using a conventional angioplasty balloon system. The disclosed stent can serve as a temporary scaffold for coronary vessels after PTCA or for peripheral endovascular stenting, or it can provide mechanical palliation for strictures of ductile organs (trachea, esophagus, bile and pancreatic ducts, ureter etc.). The disclosed stent also serves as a unique device for specific local drug delivery. Therapeutic agents (chemical compounds, protein enzyme and DNA sequences) and cells can be loaded into the stent and gradually released to target tissues. Local radiation therapy can also be delivered by a specially adapted stent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.