Use of hydrophobic crosslinking agents to prepare crosslinked biomaterial compositions
US7129209B2 · kind B2 · utility
71Cited by
11References
22Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 28, 2003 |
| Grant date | Oct 31, 2006 |
| Priority date | — |
| Expiry date | Sep 2, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/06
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention discloses novel crosslinked biomaterial compositions which are prepared using hydrophobic polymers as a crosslinking agent. Preferred hydrophobic polymers are those that contain two or more reactive succinimidyl groups, including disuccinimidyl suberate, bis(sulfosuccinimidyl)suberate, and dithiobis(succinimidyl)propionate. Crosslinked biomaterial compositions prepared using mixtures of hydrophobic and hydrophilic crosslinking agents are also disclosed. The compositions of the present invention can be used to prepare formed implants for use in a variety of medical applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.