Catalytic antioxidants and methods of use
US7129374B2 · kind B2 · utility
7Cited by
2References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 26, 2003 |
| Grant date | Oct 31, 2006 |
| Priority date | — |
| Expiry date | Mar 3, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.