Patent · US Expired

Method for the treatment of chemonucleolysis

US7132098B2 · kind B2 · utility

3Cited by

4References

20Claims

0Family size

Inventors

Koichi Masuda · Tokyo, JP
Eugene Thonar · Lockport, US
Howard An · Glenview, US

Key dates

Filing date	Feb 24, 2003
Grant date	Nov 7, 2006
Priority date	—
Expiry date	Jun 11, 2023

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a method of treatment for a mammal in need of chemonucleolysis. The method comprising the administration of an effective proteoglycan cleaving amount of a proteoglycan-degrading enzyme and an effective amount of a growth factor effective in promoting the synthesis of a matrix component. The proteoglycan-degrading enzyme is preferably chondroitinase. The growth factor is preferably osteogenic protein. The proteoglycan-degrading enzyme and the growth factor are preferably administered simultaneously.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.