DNA vaccine containing tumor-associated gene and cytokine gene and method of preparation the same
US7132407B2 · kind B2 · utility
1Cited by
2References
5Claims
0Family size
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Key dates
| Filing date | Sep 16, 2003 |
| Grant date | Nov 7, 2006 |
| Priority date | — |
| Expiry date | Apr 16, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a DNA vaccine and the method of preparation preparing the same, which employs DNA recombination technique to co-incorporate a fragment of tumor-associated gene and a fragment of cytokine gene into a vector. The administration of such DNA vaccine can enhance the immune response of the host through the co-expression of tumor-associated protein and cytokine, and thereby achieve the therapeutic effect of inhibiting or retarding tumor growth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.