Patent · US Expired

Tricyclic compounds protein kinase inhibitors for enhancing the efficacy of anti-neoplastic agents and radiation therapy

US7132533B2 · kind B2 · utility

15Cited by
4References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 22, 2005
Grant dateNov 7, 2006
Priority date
Expiry dateAug 6, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Protein kinase, such as CHK-1, inhibiting tricyclic compounds of the following formula (wherein R2, R3 and R4 are as defined in the specification)pharmaceutical compositions containing effective amounts of said compounds or their salts are useful as a single agent or in combination with an anti-neoplastic agent or therapeutic radiation having an anti-neoplastic effect for treating diseases or conditions such as cancers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.