Process for preparing hexahydropyridazine-3-carboxylic acid derivatives
US7132535B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2004 |
| Grant date | Nov 7, 2006 |
| Priority date | — |
| Expiry date | Jun 27, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D237/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
According to the process of the invention, the hexahydropyridazine-3-carboxylic acid derivatives are prepared by reacting a compound of formula (II)with a compound of formula (III)in the presence of a base with a pK of greater than or equal to 8.5, in a ketone organic solvent, to obtain an intermediate compound that is not isolated and that is treated with a basic aqueous medium.By means of this process, the derivatives are obtained more quickly and more economically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.