Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof
US7135039B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2001 |
| Grant date | Nov 14, 2006 |
| Priority date | — |
| Expiry date | Mar 6, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T29/49996
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The radially expandable prosthesis for implantation in a lumen comprises a tubular wall produced from sheet metal and showing cuts enabling the prosthesis to expand. By using water guided laser cutting technology to make these cuts and/or specific electrochemical polishing technology a more biocompatible prosthesis is obtained, causing less thrombogenicity and less foreign body reaction. By covering an intraluminal prosthesis with a titaniumnitride coating the biocompatibility of the prosthesis is improved. By applying perforating or non-perforating holes (4) and filling these holes with a therapeutic agent, the intraluminal prosthesis can be used to locally administer medicines, genes and or other substances to prevent in this way thrombotic occlusions and/or neointimal hyperplasia and prosthesis narrowing. Using this specific perforated prosthesis design the total drug capacity can be increased and also the drug release time prolongs significantly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.