Methods for controlling the lysis of coagulated blood with apolipoprotein e4 phenotype
US7135305B2 · kind B2 · utility
0Cited by
2References
27Claims
0Family size
Inventors
Key dates
| Filing date | Oct 12, 2001 |
| Grant date | Nov 14, 2006 |
| Priority date | — |
| Expiry date | Jan 27, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of lysis-inhibiting amounts of apolipoprotein E4, and methods for inhibiting lysis of coagulated blood and reducing risk of excessive lysis comprising administration of a specific level of a lysis-inhibiting agent wherein the specific level is based on the apolipoprotein phenotype of an individual, are provided. Methods for enhancing lysis of coagulated blood by administration of an Apo E peptide fragment to blood containing a clot lysis agent are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.