Patent · US Expired

Aldehyde dehydrogenase gene

US7135315B2 · kind B2 · utility

32Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 22, 2003
Grant dateNov 14, 2006
Priority date
Expiry dateSep 22, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P7/60
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to a novel DNA which encodes aldehyde dehydrogenase (SNDH), an expression vector containing the DNA and recombinant organisms containing said DNA. Furthermore, the present invention concerns a process for producing recombinant aldehyde dehydrogenase protein and a process for producing L-ascorbic acid (vitamin C) and/or 2-keto-L-gulonic acid (2-KGA) from L-sorbosone by using the recombinant aldehyde dehydrogenase protein or recombinant organisms containing the expression vector. Also provided is a process for the production of 2KGA with a microorganism in which the gene encoding said aldehyde dehydrogenase is disrupted.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.