Pyrrolopyrimidines and related analogs as HSP90-inhibitors
US7138402B2 · kind B2 · utility
11Cited by
35References
68Claims
0Family size
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Key dates
| Filing date | Sep 20, 2004 |
| Grant date | Nov 21, 2006 |
| Priority date | — |
| Expiry date | Nov 17, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds represented by Formula I. R0 is selected from hydrogen, halogen, lower alkyl, —SR8, —OR8, —CN, and —NHR8, R1 is halogen, or lower alkyl; R2 is —NHR8; R3 is selected from the group consisting of hydrogen, halogen, —SR8, —OR8, —CN, —C(O)R9, —C(O)OH, —NO2, —NR8R10, lower alkyl, lower alkenyl, lower alkynyl, lower perhaloalkyl, aryl, heteroaryl, alicyclic and heterocyclic, all optionally substituted, and R5 is aryl, heteroaryl, alicyclic, or heterocyclic:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.