Heterocyclically substituted benzoylureas, process for their preparation and their use as pharmaceuticals

US7138414B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Karl Schoenafinger · Alzenau, DE
• Elisabeth Defossa · Idstein, DE
• Dieter Kadereit · Kelkheim, DE
• Erich Von Roedern · Hattersheim, DE
• Thomas Klabunde · Frankfurt, DE
• Hans-Joerg Burger · Morristown, US
• Andreas Herling · Bad Camberg, DE
• Karl-Ulrich Wendt · Frankfurt, DE

Key dates

• Filing date: Jul 11, 2003
• Grant date: Nov 21, 2006
• Expiry date: Jul 11, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/68
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to heterocyclically substituted benzoylureas and also to their physiologically tolerated salts and physiologically functional derivatives.Compounds are described of the formula Iwhere the radicals are defined as specified, and also their pharmaceutically acceptable salts and processes for their preparation. The compounds are suitable, for example, for treating type 2 diabetes.