Thiolalkyl benzoic acid derivatives
US7138543B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Apr 7, 2004 |
| Grant date | Nov 21, 2006 |
| Priority date | — |
| Expiry date | Aug 9, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to new thiolalkyl benzoic acids, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers, glaucoma, retinal disorders, and cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.