Method and apparatus for separating ions of metallic elements in aqueous solution
US7138643B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 22, 2004 |
| Grant date | Nov 21, 2006 |
| Priority date | — |
| Expiry date | Apr 23, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G2001/0094
- WIPO fieldEngines, pumps, turbines
- WIPO sectorMechanical engineering
Abstract
Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation. Also described is a new 99mTc generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers designed to selectively absorb 99Mo at a selected pH, t…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.