Use of liquid junction potentials for electrophoresis without applied voltage in a microfluidic channel
US7141429B2 · kind B2 · utility
24Cited by
2References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 9, 2002 |
| Grant date | Nov 28, 2006 |
| Priority date | — |
| Expiry date | Apr 19, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/118339
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention provides methods for using liquid junction potentials to control the transport of charged particles in fluid streams that are in laminar flow within microfluidic channels. Applications of the methods of this invention include sample preconditioning (removal of interfering substances), electrophoretic separation (fractionation) of charged particles, enhanced or delayed mixing of charged particles across a fluid interface relative to diffusion only, focusing charged particles in a fluid stream in one or two dimensions, and concentration of charged reactants at a fluid interface.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.