2-(substituted-phenyl)amino-imidazoline derivatives

US7141584B2 · kind B2 · utility

Assignee

• Roche Palo Alto LLC · US

Inventors

• Keith R. Bley · Menlo Park, US
• Robin Clark · Palo Alto, US
• Alam Jahangir · San Jose, US
• Bruce Andrew Kowalczyk · Cupertino, US
• Francisco Javier Lopez-Tapia · Mahwah, US
• Alexander Victor Muehldorf · Sunnyvale, US
• Counde O'Yang · Sunnyvale, US
• Thomas Sun · Fremont, US

Key dates

• Filing date: Dec 9, 2003
• Grant date: Nov 28, 2006
• Expiry date: Dec 9, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I:where: and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.