Process for the preparation of (pyrimidin-2-yl) methyl ketones
US7145007B2 · kind B2 · utility
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1References
13Claims
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Key dates
| Filing date | Oct 9, 2002 |
| Grant date | Dec 5, 2006 |
| Priority date | — |
| Expiry date | Feb 4, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation, of (pyrimidin-2-yl)methyl ketones of the general formula (I),in which R1 is in each case a C1-10-alkyl group, a C3-8-cycloalkyl group, an allyl group or an aryl-C1-4-alkyl group, and R2 is a C1-10-alkyl group or aryl group. For this, a malondiimidate of the general formula (II),in which R1 has the meaning given above, is reacted with a β-keto ester of the general formula (III),in which R2 has the meaning given above, and R3 is a C1-10-alkyl group. The compounds which can be prepared according to the invention are intermediates for the synthesis of agrochemical active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.