Rapidly disintegrating tablet comprising an acid-labile active ingredient

US7147869B2 · kind B2 · utility

Assignee

• ALTANA PHARMA AG · DE

Inventors

• Rango Dietrich · Konstanz, DE
• Hartmut Ney · Konstanz, DE
• Rudolf Linder · Konstanz, DE

Key dates

• Filing date: Dec 6, 2001
• Grant date: Dec 12, 2006
• Expiry date: Mar 29, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A rapidly disintegrating tablet for oral administration of acid-labile active ingredients is described. The rapidly disintegrating tablet for oral administration of an acid-labile active ingredient comprises a plurality of individual active ingredient units together with pharmaceutical excipients, where the acid-labile active ingredient is present in the individual active ingredient units in a matrix composed of a mixture comprising at least one solid paraffin and one or more substances from the group of fatty alcohol, triglyceride and fatty acid ester, and where excipients which, on oral intake of the tablet, bring about rapid disintegration of the tablet are present.