Platelet-derived growth factor D, DNA coding therefor, and uses thereof

US7148037B2 · kind B2 · utility

Assignees

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB
• Licentia Group Limited · FI

Inventors

• Ulf Eriksson
• Karin Aase · Stockholm, SE
• Xuri Li · Stockholm, SE
• Annica Ponten · Stockholm, SE
• Marko Uutela · Helsinki, FI
• Kari Alitalo · Helsinki, FI
• Arne Oestman · Uppsala, SE
• Carl-Henrik Heldin · Uppsala, SE

Key dates

• Filing date: Mar 4, 2002
• Grant date: Dec 12, 2006
• Expiry date: Jul 7, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

PDGF-D, a new member of the PDGF/VEGF family of polypeptide growth factors, is described, as well as nucleotide sequences encoding, methods for producing, pharmaceutical compositions containing this new growth factor, and its antibodies and other antagonists. Also disclosed are transfected and transformed host cells expressing PDGF-D, and uses thereof in medical and diagnostic applications.