Monomer addition techniques to control manufacturing of bioabsorbable copolymers
US7148315B2 · kind B2 · utility
24Cited by
33References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 23, 2002 |
| Grant date | Dec 12, 2006 |
| Priority date | — |
| Expiry date | Oct 23, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G63/64
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Monomer addition methodology is provided to adjust monomer addition rates to a polymerization reactor. Advantages of the invention include control of bioabsorbable copolymer structure, improvement of monomer conversion, control of reaction temperature, and reduced reaction time. The overall result is an improved process and enhanced product performance. The technology is particularly useful in the copolymerization of monomers with different reactivity ratios, such as glycolide/lactide copolymers and glycolide/caprolactone copolymers. Monomer reactivity ratios and reaction kinetics are utilized to adjust monomer addition rates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.