Neutral self-setting calcium phosphate paste
US7150879B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 2000 |
| Grant date | Dec 19, 2006 |
| Priority date | — |
| Expiry date | Jul 6, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/58
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature an is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.