Dielectrophoretic separation of stained cells
US7153648B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 20, 2002 |
| Grant date | Dec 26, 2006 |
| Priority date | — |
| Expiry date | Apr 10, 2023 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB03C5/005
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
This invention relates generally to the field of cell separation or isolation. In particular, the invention provides a method for separating cells, which method comprises: a) selectively staining cells to be separated with a dye so that there is a sufficient difference in a separable property of differentially stained cells; and b) separating said differentially stained cells via said separable property. Preferably, the separable property is dielectrophoretic property of the differentially stained cells and the differentially stained cells are separated or isolated via dielectrophoresis. Methods for separating various types of cells in blood samples are also provided. Centrifuge tubes useful in density gradient centrifugation and dielectrophoresis isolation devices useful for separating or isolating various types of cells are further provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.