Marburg I mutant of factor VII activating protease (FSAP) as risk factor for arterial thrombosis

US7153679B2 · kind B2 · utility

Assignee

• Aventis Behring GmbH · DE

Inventors

• Stefan Kiechl · Zirl, AT
• Johann Willeit · Innsbruck, AT
• Christian Wiedermann · Innsbruck, AT
• Juergen Roemisch · Marburg, DE
• Thomas Weimer · Gladenbach, DE
• Annette Feussner · Marburg, DE
• Hans-Arnold Stoehr · Wetter, DE
• Volker Doersam · Marburg, DE
• Wiegand Lang · Cölbe, DE
• Margret Becker · Marburg, DE
• Claudia Nerlich · Marburg, DE
• Gudrun Muth-Naumann · Wetter, DE
• Bernd Knoblauch · Lich, DE

Key dates

• Filing date: Mar 19, 2003
• Grant date: Dec 26, 2006
• Expiry date: Mar 19, 2023

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/323
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A novel arterial thrombosis risk factor comprising one or more of the identified mutants of coagulation factor VII-activating protease (FSAP) is described. In addition, diagnostic determination methods for detecting these mutants which are identified as risk factors are described.