Compositions and methods for modulating connexin hemichannels
US7153822B2 · kind B2 · utility
26Cited by
50References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2003 |
| Grant date | Dec 26, 2006 |
| Priority date | — |
| Expiry date | Jul 12, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/326
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions and methods for modulating hemichannel function in a cell, tissue or organ. The invention also relates to useful screens for detecting such compounds, particularly those capable of modulating connexin phosphorylation. Further provided are therapeutic methods for preventing or treating conditions impacted by undesired hemichannel function in a mammal such as heart arrhythmia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.