Substituted amino acids as erythropoietin mimetics

US7153869B2 · kind B2 · utility

Inventors

• Peter J. Connolly · New Providence, US
• Victor T. Bandurco · Bound Brook, US
• Steven K. Wetter · Flemington, US
• Sigmond Johnson · Flemington, US
• Jacqueline Bussolari · Skillman, US
• William V. Murray · Montgomery, US

Key dates

• Filing date: Mar 12, 2004
• Grant date: Dec 26, 2006
• Expiry date: May 21, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to a series of substitituted amino acids of Formula Ipharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoietin receptor and compete with the natural ligand for binding to this receptor.