Compounds acting as melanocortin receptor ligands

US7153881B2 · kind B2 · utility

Assignee

• ACURE PHARMA AB · SE

Inventors

• Torbjorn Lundstedt · Bjärred, SE
• Anna Skottner · Ekerö, SE
• Arne Boman · Strömsund, SE
• Per Andersson · Lund, SE
• Victor Andrianov · Rīga, LV
• Ivars Kalvins · Ikšķile, LV

Key dates

• Filing date: Aug 7, 2001
• Grant date: Dec 26, 2006
• Expiry date: Aug 15, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides novel compounds and use of compounds of general formula (I) as ligands to the melanocortin receptors and/or for treatment of disorders in the melanocortin system: Wherein X and Y are independently chosen from O, N, S and (CH2)n, where n is 0, 1, 2, 3, 4, or 5, or a combination of these and may contain carbon-carbon multiple bonds and branched chains as well as alicyclic and heterocyclic groups; Q is H or OH; R1 and R2 can be either the same or different and are chosen from hydrogen or the residue of an aromatic group as listed in Scheme 1 and the pharmacologically active salts thereof