Target molecules detection by waveguiding in a photonic silicon membrane

US7155076B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Sonia Letant · Benicia, US
• Anthony W. Van Buuren · Livermore, US
• Louis Terminello · Pleasanton, US
• Bradley R. Hart · Brentwood, US

Key dates

• Filing date: Apr 27, 2004
• Grant date: Dec 26, 2006
• Expiry date: Jul 30, 2024

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/7783
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Disclosed herein is a porous silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and calculate the concentration of bound target.