Method and kit for identifying and/or quantifying radiolabeled aminoglycoside binding molecules
US7157239B2 · kind B2 · utility
0Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2002 |
| Grant date | Jan 2, 2007 |
| Priority date | — |
| Expiry date | Aug 22, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/48
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention describes novel methods, assays and kits for identifying and/or quantifying Aminoglycoside Binding Molecules (ABMs), enzymes modifying such molecules, and compounds modulating the interaction between ABMs and either enzymes or aminoglycosides, by exploiting the scintillation proximity effect. The invention, which makes use of aminoglycoside-coated scintillating supports, can be adapted to high throughput screening formats.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.