Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders

US7157425B2 · kind B2 · utility

Assignees

• Jean-Louis Dasseux · US
• Renate Sekul · DE
• Klaus Buttner · DE
• Isabelle Cornut · CH
• Gunther Metz · DE
• Jean DuFoureq · FR

Inventors

• Jean-Louis Dasseux · Mannheim, DE
• Renate Sekul · Ladenburg, DE
• Klaus Büttner · Epfenbach, DE
• Isabelle Cornut · Edingen-Neckarhausen, DE
• Günther Metz · Edingen-Neckarhausen, DE

Key dates

• Filing date: Mar 15, 2002
• Grant date: Jan 2, 2007
• Expiry date: Jan 14, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.