Patent · US Expired

Heterocyclic dihydropyrimidine compounds

US7157451B2 · kind B2 · utility

59Cited by
5References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 12, 2003
Grant dateJan 2, 2007
Priority date
Expiry dateSep 12, 2023

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel heterocyclic dihydropyrimidine compounds useful as inhibitors of potassium channel function (especially inhibitors of the Kv1 subfamily of voltage gated K+ channels, especially inhibitors Kv1.5 which has been linked to the ultra-rapidly activating delayed rectifier K+ current IKur), methods of using such compounds in the prevention and treatment of arrhythmia and IKur-associated conditions, and pharmaceutical compositions containing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.