Method for synthesizing derivatives of (2S,3AS,7AS)-1-[(S)-alanyl]-octahydro,-1H-indole-2-carboxylic acid and the use thereof for perindopril synthesis
US7157485B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Feb 27, 2004 |
| Grant date | Jan 2, 2007 |
| Priority date | — |
| Expiry date | Mar 4, 2024 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Process for the synthesis of compounds of formula (I):wherein R1 represents hydrogen, alkyl or benzyl and R2 represents a protecting group for the amine function.Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.