Patent · US Expired

Bioprocess for the production of recombinant anti-botulinum toxin antibody

US7157562B1 · kind B1 · utility

17Cited by
5References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 14, 2003
Grant dateJan 2, 2007
Priority date
Expiry dateOct 8, 2024

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/867
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A process for producing recombinant anti-botulinum toxin antibody comprising the steps of fermenting recombinant E. Coli cells in broth, concentrating the cells by removing the broth, crushing the concentrated cells, separating a permeate derived from the crushed cells from cell debris, purifying a recombinant antibotulinum antibody (Fab) from said permeate, and separating said Fab from impurities by diafiltration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.