Streptococcal streptolysin S vaccines
US7160547B2 · kind B2 · utility
4Cited by
3References
21Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 9, 2002 |
| Grant date | Jan 9, 2007 |
| Priority date | — |
| Expiry date | Nov 14, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/1275
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are streptolysin S (SLS) polypeptides, peptides, and variants thereof, antibodies directed thereto, and isolated nucleic acids encoding such proteins. In one embodiment, a method is provided wherein a synthetic peptide of SLS is used to elicit an immune response specific for SLS in a subject to treat or prevent a streptococcal infection. In other embodiments, antibodies that neutralize the hemolytic activity of the SLS toxin may be used as a vaccinating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.