α-O-linked glycoconjugates, methods of preparation and uses thereof
US7160856B2 · kind B2 · utility
11Cited by
22References
47Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2002 |
| Grant date | Jan 9, 2007 |
| Priority date | — |
| Expiry date | Feb 6, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel α-O-linked glycoconjugates such as α-O-linked glycopeptides, as well convergent methods for synthesis thereof. The general preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the α-O-linked glycoconjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.