Hydroxyethylene compounds with Asp2 inhibitory activity
US7160905B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Nov 29, 2002 |
| Grant date | Jan 9, 2007 |
| Priority date | — |
| Expiry date | Mar 1, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel hydroxyethylene compounds having Asp2 (β-secretase. BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.