Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
US7163694B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Mar 8, 2006 |
| Grant date | Jan 16, 2007 |
| Priority date | — |
| Expiry date | Mar 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G2650/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block copolymers contain these bioerodible poly(ortho esters). These block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them suitable for encapsulation or solubilization of hydrophobic or water-insoluble materials; and they also form bioerodible matrices for the sustained release of active agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.