Patent · US Expired

Macrocyclic metal complexes and their use for the production of conjugates with biomolecules

US7164016B2 · kind B2 · utility

1Cited by

6References

23Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Johannes Platzek · Berlin, DE
Heribert Schmitt-Willich · Berlin, DE
Gunther Michl · Bornheim, DE
Thomas Frenzel · Berlin, DE
Detlev Sülzle · Berlin, DE
Hans Bauer · Dana Point, US
Bernd Raduchel · Berlin, DE
Hanns-Joachim Weinmann · Berlin, DE
Heiko Schirmer · Solingen, DE

Key dates

Filing date	Jul 19, 2002
Grant date	Jan 16, 2007
Priority date	—
Expiry date	Nov 16, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D257/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to macrocyclic metal complexes and their production and use for the production of conjugates with biomolecules. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.