Opiate analogs selective for the δ-opioid receptor
US7164021B2 · kind B2 · utility
2Cited by
9References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 18, 2003 |
| Grant date | Jan 16, 2007 |
| Priority date | — |
| Expiry date | Jun 23, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds which selectively bind to the δ-opioid receptor have been designed. These compounds have greater selectivity, improved water (blood) solubility, and enhanced therapeutic value as analgesics. Because agonists with selectivity for the δ-opioid receptor have shown promise in providing enhanced analgesis without the addictive properties, the compounds of the present invention are better than morphine, naltrindole (NTI), spiroindanyloxymorphone (SIOM), and other known μ-opioid receptor selectors as analgesics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.