Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate

US7164023B2 · kind B2 · utility

Assignee

• Wockhardt Limited · IN

Inventors

• Prasad Keshav Deshpande · Aurangabad, IN
• Vijaya Narayan Desai · Aurangabad, IN
• Ravindra Dattatraya Yeole · Aurangabad, IN
• Shrikant Gupte · Aurangabad, IN
• Mahesh Vithalbhai Patel · Aurangabad, IN
• Noel De Souza · Mumbai, IN

Key dates

• Filing date: Dec 31, 2003
• Grant date: Jan 16, 2007
• Expiry date: Dec 31, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to crystalline S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid L-arginine salt tetrahydrate, a process for its preparation and pharmaceutical formulations incorporating it as the active ingredient for use in treating microbial infections.