Prodrugs of DP IV-inhibitors

US7166579B2 · kind B2 · utility

Assignee

• Prosidion Limited · GB

Inventors

• Hans-Ulrich Demuth · Halle (Saale), DE
• Dagmar Schlenzig · Bodenwerder, DE
• Torsten Hoffmann · Weil am Rhein, DE
• Susanne Manhart · Halle (Saale), DE

Key dates

• Filing date: Dec 11, 2003
• Grant date: Jan 23, 2007
• Expiry date: Feb 10, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Prodrug compounds of unstable inhibitors of the serine peptidase dipeptidyl peptidase IV, are used in the treatment of various disorders, especially of metabolic disorders. The Prodrug compounds can be used in the treatment of impaired glucose tolerance, glucosuria, hyperlipidaemia, metabolic acidoses, diabetes mellitus, diabetic neuropathy and nephropathy.