Patent · US Expired

24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3

US7166585B2 · kind B2 · utility

19Cited by
1References
20Claims
0Family size

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Key dates

Filing dateJul 3, 2003
Grant dateJan 23, 2007
Priority date
Expiry dateMar 3, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C401/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides novel C24-sulfone analogs of 1α,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as selective inhibitors of CYP24. In particular, the compounds of the invention are useful for treating diseases which benefit from a modulation of the levels of 1α,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.