Substituted indolinones, preparation thereof and their use as pharmaceutical compositions

US7166615B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Rainer Walter · Biberach, DE
• Armin Heckel · Biberach an der Riß, DE
• Gerald Juergen Roth · Biberach, DE
• Joerg Kley · Mittelbiberach, DE
• Gisela Schnapp · Biberach an der Riß, DE
• Martin Lenter · Ulm, DE
• Jacobus Van Meel · Biberach, DE
• Walter Spevak · Stockerau, AT
• Ulrike Weyer-Czernilofsky · Baden, AT

Key dates

• Filing date: Aug 22, 2003
• Grant date: Jan 23, 2007
• Expiry date: Apr 17, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Indolinones of general formula Iwhich are inhibitors of cell proliferation, particularly of tumor cells, and inhibitors of protein kinases.