Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells
US7166694B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Apr 12, 2001 |
| Grant date | Jan 23, 2007 |
| Priority date | — |
| Expiry date | Aug 19, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for producing a vaccine against cancerous disease, and the vaccine itself. This method involves first using one or more antibodies that are specifically effective against one or more antigens specially expressed by the tumor cells to select one or more mimotopes of said antigens from a phage peptide library. To obtain the vaccine, said mimotopes are conjugated to a macromolecular carrier singly or multiply in the form of their mono-, di-, tri- or oligomers. When administered, the inventively produced vaccine leads to a humoral immune response and thus to the formation of an active immunity as a consequence of vaccination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.