Patent · US Expired

V-like domain binding molecules

US7166697B1 · kind B1 · utility

39Cited by
12References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 5, 1999
Grant dateJan 23, 2007
Priority date
Expiry dateMar 5, 2019

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/812
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterized in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.