Mouse model of myxomatous valvular disease
US7166763B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Feb 10, 2003 |
| Grant date | Jan 23, 2007 |
| Priority date | — |
| Expiry date | Feb 10, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/32
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An animal selected for lacking heparan sulfate 3-O-sulfotransferase-1 activity is provided. This animal exhibits characteristics associated with myxomatous valvular disease and is useful for identifying agents which prevent, delay or treat myxomatous valvular disease. Methods of diagnosing myxomatous valvular disease are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.