Screening assay utilizing the PTH receptor
US7169567B1 · kind B1 · utility
11Cited by
8References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 31, 1998 |
| Grant date | Jan 30, 2007 |
| Priority date | — |
| Expiry date | Dec 31, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/72
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides a novel PTH receptor polypeptide, rΔNt, characterized by a deletion of the extracellular amino-terminus, ligand binding domain of the receptor. Additionally disclosed are nucleic acid molecules encoding the receptor. The receptor has a minimal domain for ligand binding and is useful in screening assays designed for the identification of agonists and antagonists of PTH receptor activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.